Edibles and Recipes: Decarboxylation, Infusion and Dose Control

Cooking with cannabis, treated as chemistry with a kitchen attached: decarboxylation, infusion into fat or alcohol, why an edible behaves so differently from inhalation, and how anyone is supposed to know what a dose is in a pan of brownies.

Two conversions decide the result. Heat converts the acid forms in raw plant material into the neutral cannabinoids that are active, and too much heat destroys what it just made; then the infusion step moves those molecules into a fat or an alcohol, because they will not go into water. Almost every disappointing edible failed at one of those two steps.

Two things about dose belong in every recipe thread. An oral dose passes through the liver first and produces a different, slower and usually stronger effect than inhalation, arriving late enough that people take a second helping before the first one lands. And a home infusion has no assay behind it, so a recipe that states milligrams per portion is stating an estimate: say so, and divide accordingly.

Where to start

Related elsewhere on the forum: Routes of Administration for Medical Cannabis in Medical Cannabis.